Liquid Chromatography-Mass Spectrometry LZ-LCMS-A100 delivers ultra-trace detection for pharmaceutical, environmental, and food safety testing. Its triple quadrupole mass analyzer pairs with an automatic sample injector supporting up to 384 positions, backed by a column oven that holds six 250mm columns at once. Detection reaches 1pg on-column sensitivity with signal-to-noise above 100,000:1 — well suited for residue screening, drug metabolite profiling, and multi-compound quantitation in complex sample matrices.
| Specification | Value |
|---|---|
| Gradient Pump Solvent Selection | Two-solution selection (A/B or C/D) via automated selection valve. |
| Gradient Pump Degassing System | Integrated vacuum degasser |
| Gradient Pump Flow Rate | 1 to 4,000 µL/min. |
| Gradient Pump Maximum Operating Pressure | ≥ 18,850 psi. |
| Gradient Pump Accuracy | ≤ 1%. |
| Gradient Pump Precision | ≤ 0.075% RSD. |
| Automatic Sample Injector Modes | Full loop injection, partial loop injection, and microliter pickup. |
| Automatic Sample Injector Repeatability | Full loop injection: < 0.3% RSD; Partial loop injection: < 0.3% RSD; Microliter pickup: < 1.0% RSD. |
| Automatic Sample Injector Cross-Contamination | < 0.05%. |
| Column Oven Sample Capacity | 384 positions (bits), and 96 positions (bits) for standard liquid injection. |
| Column Oven Temperature Control Range | RT +5 °C to 90 °C. |
| Column Oven Temperature Control Mode | Flowing phase preheating + forced air circulation. |
| Maximum Column Capacity | Up-to six 250 mm chromatographic columns |
| Ion Source Design | Orthogonal vertical spray |
| Ion Source Gas Supply Requirements | 1 loop of nitrogen for atomizing (0–2 L/min); 2 loops of nitrogen for desolvation (0–15 L/min). |
| Blowback Gas Design | High-temperature nitrogen blowback (0–5 L/min) |
| Interface Heating | 110 °C |
| Ion Optics | 4-stage differential vacuum design with multi-quadrupole transmission |
| Mass Analyzer Type | Triple quadrupole mass analyzer. |
| MS-Quadrupole Material | High-precision pure Molybdenum (Mo) |
| MS-Cell | Collision Cell |
| Mass Resolution | 0.4 to 2 amu (user-adjustable). |
| Mass Stability | Better than 0.1 amu over 24 hours. |
| Mass Analyzer Scanning Speed | ≥ 20,000 amu/s. |
| Mass Range m/z | 5 - 1,000 amu. |
| Mass Analyzer Dynamic Range | 6 orders of magnitude. |
| Mass Analyzer Sensitivity | ESI+, MRM mode: 1pg reserpine on-column, S/N ≥ 100,000:1; ESI-, MRM mode: 1pg chloramphenicol on-column, S/N ≥ 100,000:1. |
| Scanning Functions | Full scan, selected ion monitoring (SIM), product ion scan, precursor ion scan, neutral loss scan, multiple reaction monitoring (MRM), positive/negative ion switching scan, etc. |
| Detector Technology | Multiplier technology |
| Detector Type | Pulse-counting detector |
| Detector Polarity Switching Time | ≤ 50 ms (Positive/negative polarity switching). |
| Vacuum System | Composed of a mechanical pump and a turbo molecular pump with a differential pumping system |
| Power Supply | Five sets of single-phase AC(220 ± 20) V, 10A, 50 Hz |
| Product Dimensions | 1000×700 ×600mm |
| Packing Dimensions |
1400×680×920mm 1570×970×1020mm 810×700×790mm |
| Gross Weight | 430 kg |
Liquid Chromatography-Mass Spectrometry is used to evaluate drug pharmokinetics, detect inborn errors of metabolism, peptide identification, trace harmful pollutants, pesticides, toxins, and chemical contaminants.
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